Coronavirus

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Coronavirus

“Coronavirus; A Result Of Wildlife Invasion”

Coronavirus Nowadays waking up with a little throat pain in the morning strikes panic over you; have I been infected with coronavirus? You may even review a list of friends and families who sneezed occasionally in your presence or coughed slightly. Since many people have been affected and even died, it is only natural to panic about this epidemic viral infection.   Why is it the worse epidemic? This epidemic started out to be recognized in early Dec 2019. Although most of heard about after the new years of 2020 when the situation started to go out of hand. Since we are mentally prepared to panic for a viral breakout every few years, this one seems to have its odds a little stronger. Coronavirus is similar to normal flu-like symptoms with incubation of two weeks with no symptoms; which makes it a perfect medium for its silent transition. The other factor that helps the odd of spreading the virus is its start-up location. China one of the most populated countries in the world holding a population of 1.38 billion people. That is, almost 20 percent of everyone on this planet is in close contact with the virus. Last, but not the least, is china’s trade with every single country; there many entrepreneurs that are on the daily flights in and out of China. In the same way, many Chinese have been moving out of china for means of business before and after the epidemic spread. All of these factors put together gives a perfect chance to the virus to introduce itself to healthy bodies across the world.   If following the root cause of the virus, we reach to the good markets of Wuhan. Chinese has a reputation for its known- animal right friendly food markets. There is uncontrolled meat distribution among Chinese shoppers. Needless to say, the species varieties found in these large markets. Although this unwelcome guest imposing as a new disease is not so unfamiliar. There was a bat found in one of the Caves of Yunnan province. Many of the reserves who studies on this bat noticed for potential risks and deadly outcomes from these particular bats. Today we are here on the verge of a decade started out with coronavirus that was warned about years ago. However, the rising number of the victims, isolated suspects and panic of its viral spread is upsetting, yet not too unexpected.   The bat’s species and pangolins A few scientists conducted extensive research through 5 consecutive years and the fecal matter of these bats. The results showed that four variables of bat speed were carriers of coronavirus. One of the bat species is known as the horseshoe bat. While suggested supporting documents about the carrier bats, there are other suspects in this trial. Researchers wondered how the bats have transferred their disease to humans; seeking a missing link between the two led them. While bat-borne virus lacked features to infect human beings, there must have been a translator of this virus to the human body; an endangered species of pangolin has been pointed as the most possible transmitter. However, there may be other links involved. The reason is the presence of many capable transmitters of the disease.   Prevention of future deaths While there are many species that are considered transmitters of coronavirus, they all have one thing in common; they are not farm grown animals. Rather all of these possible transmitters live in the wildlife. Having a specific guess or generalized category of where coronavirus has come from and endangered the human species is; the wild animal food markets. These markets in china are considered illegal by the Chinese government. However, the large spaces proved to the illegal food markets show little interest in the government to ban such trades. Some of these markets have to face practical prohibition, although only after the outbreak had taken place.   The scientist is enlisting the name of the possible animals that have been possible the reason for this transmission. Many researchers are trying to find the medications which are combinations of viral vaccines and HIV immune medications.   Conclusion Coronavirus’s root cause has been pointed out. However, there is not medication this far. Trying to avoid physical contact is the best way of prevention. This virus is not air bourn and required transmission through touch and surfaces.  

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Health

What People With Asthma Need to Know-Covid 19

  Asthma Patients Need to Know What became known as COVID-19, or the coronavirus, began in late 2019 as a group of pneumonia cases with an obscure reason. The cause of the pneumonia was found to be a novel virus – serious intense respiratory disorder coronavirus 2, or Sars-CoV-2. The ailment brought about by the novel is COVID-19. [su_quote]Presently announced as a pandemic by the World Health Organization (WHO), most people who contract COVID-19 suffer just mild, cold-like symptoms.[/su_quote] Presently announced as a pandemic by the World Health Organization (WHO), most people who contract COVID-19 suffer just mild, cold-like symptoms. WHO says about 80% of individuals with COVID-19 recoup without compelling any authority treatment. Only about one person in six develops seriously ill “and develops struggle breathing”. The danger of Severe Illness from COVID-19   Individuals with moderate to serious asthma might be at higher danger of becoming ill from COVID-19. COVID-19 can stimulus your respiratory tract (nose, throat, lungs), cause an asthma attack and possibly lead to pneumonia and intense respiratory sickness. COVID-19 Treatment   There is right now no particular treatment for or immunization to prevent COVID-19. The most ideal approach to prevent sickness is to avoid being exposed to this virus. If you have asthma, you are among those at most serious hazard in the coronavirus pandemic and must avoid potential risk, the American College of Allergy, Asthma, and Immunology (ACAAI) says.   It’s imperative to keep your asthma very much controlled, so proceed with your drugs. No asthma meds – including breathed in corticosteroids and biologics – have been appeared to build the danger of getting COVID-19, as per the ACAAI. Also, the gathering included, in the event that you do get the infection, there’s no data that asthma prescriptions will aggravate your disease. The ACAAI prescribes reaching your allergist on the off chance that you have any inquiries, experience difficulty breathing or your asthma indications become progressively serious. Others at higher hazard from the coronavirus incorporate the old, and individuals with immunodeficiency or other ceaseless conditions that debilitate the insusceptible framework. For the present, the ACAAI is exhorting those with asthma or who may have immunodeficiency to proceed with medicines. Nebulizers should be used and cleaned properly. It’s important that your asthma remains well-controlled. So far, 80% of coronavirus cases are mild and last for a limited time. Symptoms include fever, cough, and shortness of breath.   Asthma prescription Starting at 6 March 2020, and late update on 13 March, the Therapeutic Goods Administration (TGA) has not gotten any notices of medication deficiencies in Australia that are an immediate consequence of COVID-19. Along these lines, while it might be suitable for people to guarantee that they have in any event 30 days supply of physician endorsed meds in the far-fetched occasion they are isolated, any amassing of drugs is pointless. As well as treating your asthma, there are other easy steps everyone can take to lower risk of a viral infection. You can view these steps via video from the World Health Organisation (WHO) below. Follow your Asthma Action Plan   Monitor your asthma Proceed with your present meds, remembering any inhalers with steroids for them (“steroids” is another word for corticosteroids). Try not to stop any meds or change your asthma treatment plan without conversing with your medicinal services supplier. Talk about any worries about your treatment with your medicinal services supplier. Converse with your medicinal services supplier, back up plan, and drug specialist about making a crisis supply of doctor prescribed prescriptions, for example, asthma inhalers. Ensure that you have 30 days of non-professionally prescribed prescriptions and supplies close by too on the off chance that you have to remain at home for quite a while. Ability to utilize your inhaler. Maintain a strategic distance from your asthma triggers. As more instances of COVID-19 are found and our networks make a move to battle the spread of ailment, it is normal for certain individuals to feel concerned or focused. Compelling feelings can trigger an asthma assault. Find a way to assist yourself in adapting to pressure and nervousness. Clean and purify things you or your family contact every now and again In the event that conceivable, have somebody who doesn’t have asthma do the cleaning and sanitizing. At the point when they use cleaning and purifying items, have them:   Ensure that individuals with asthma are not in the room.   Limit the utilization of disinfectants that can cause an asthma assault.   Open windows or entryways and utilize a fan that blows air outside.   Clean and sterilize surfaces like telephones, remotes, tables, door handles, light switches, ledges, handles, work areas, consoles, toilets, fixtures, and sinks day by day. Continuously adhere to the guidelines on the item name. Shower or pour splash items onto a cleaning fabric or paper towel as opposed to showering the item straightforwardly onto the cleaning surface (if the item name permits). On the off chance that you have side effects. In essence, it means: Staying home when unwell Avoiding large public gatherings if not essential Keeping 1.5 metres from other people when possible Avoiding physical contact where possible (avoiding kissing, handshaking, hugging). Making sure you have access to your current medications and having an emergency kit prepared is good practice for any emergency situation.   Contact your medicinal services supplier to get some information about your side effects.  

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Coronavirus

Global fear of the Novel Coronavirus

Coronavirus:- What is flashing global fear of the Novel Coronavirus What is flashing global fear of the novel coronavirus –  The current outbreak of infections with a novel form of coronavirus has caused global fear and concern that the virus could spread too far and too quickly and cause drastic harm before health officials can find a way to stop it. In December last year, reports began to emerge that a coronavirus that specialists had never before seen in humans had begun to spread among the population of Wuhan, an outsized city within the Chinese province of Hubei. Since then, the virus has spread to other countries, both in and outside Asia, leading authorities to explain this as an epidemic. At the end of January this year, the World Health Organization (WHO) declared the state to be a public health emergency. To date, the novel coronavirus — currently dubbed “severe acute respiratory syndrome coronavirus 2,” or SARS-CoV-2 for brief — has been responsible for 78,191 infections in China and 2918 across 37 other world countries. In China, the virus has so far triggered 2,718 deaths. It also led to at least one fatality within the Philippines. But what can we really realize this virus? and the way is it likely to affect the worldwide population? Medical News Today has contacted the WHO, used the information that public health organizations have accessible, and checked out the most recent studies that have featured in peer-reviewed journals to answer these and other questions from our readers. What’s the new virus? SARS-CoV-2 is a coronavirus that triggers coronavirus disease in 2019 (COVID-19). Coronaviruses, generally, are a family of viruses that focus on and affect mammals’ respiratory systems. Consistent with their specific characteristics, there are four main “ranks” (genera) of coronaviruses, which are called alpha, beta, delta, and gamma. Most of these only affect animals, but few can also can pass to humans. people who are transmissible to humans belong to only two of those genera: Alpha and Beta. Only two coronaviruses have previously caused global outbreaks. The first of these was the SARS coronavirus — liable for the severe acute respiratory syndrome (SARS) — which first started spreading back in 2002, also in China. The SARS virus epidemic primarily affected the populations of China and Hong Kong, and it died off in 2003. The other one was the MERS coronavirus — or Middle East respiratory syndrome coronavirus — which emerged in Saudi Arabia in 2012. This virus has affected a minimum of 2,494 people since then.   Who to test: PHO Laboratory will accept specimens for COVID-19 testing from individuals meeting criteria for an individual under investigation (PUI) or probable case for COVID-19 as outlined by the Ministry of Health.Clinical presentations that don’t fit case definition, but are considered in danger of COVID-19 by the assessing clinician also will be accepted for testing. PHO isn’t presently endorsing routine testing of asymptomatic persons for COVID-19. Mandatory data accompanying testing requests: The following mandatory information is included on the PHO Laboratory requisition: Whether the specific meets criteria for a person under investigation (yes/ no) Travel history (country and dates) Contact of the case or probable case (yes/no); if no, other sick contacts (yes/no; if yes, describe) Symptom onset date Clinical information (e.g. fever, cough, rhinorrhea, pneumonia) Patient setting (inpatient – ICU or ward, hospitalized, ER not admitted, physician office/clinic, institution or outpatient) Specimen collection recommendations: A) Patients not admitted to hospital (including those in ER) A single upper respiratory tract specimen will be accepted for COVID-19 testing. Upper respiratory tract specimens include a nasopharyngeal swab (NPS) OR viral throat swab collected in universal transport medium. NPS is preferred over a viral throat swab – information available to date suggests that an NPS has higher sensitivity than a throat swab for COVID-19 detection. B) In-patients For in-patients, it is recommended to collect a  minimum of two specimens, from two different sites: Upper respiratory tract: submit both a nasopharyngeal swab (NPS) AND viral throat swab collected in the universal transport medium. Lower respiratory tract specimens: submit when possible. Sputum: collect if the patient has a productive cough. Do not induce. Serology for COVID-19 is not available. Where did the virus originate? When humans do become infected with a coronavirus, this typically occurs via contact with an infected animal. Some of the most common transporters are bats, although they are doing not typically transmit coronaviruses on to  Instead, the transmission might occur via an “intermediary” animal, which can usually — though not always — be a domestic one. The SARS coronavirus increases to humans via civet cats, while the MERS virus spread via dromedaries. However, it is often difficult to work out the animal from which a coronavirus infection first starts spreading. In the case of the novel coronavirus, initial reports from China tied the outbreak to a seafood market in central Wuhan. As a result, local authorities closed down the market on January 1. However, later assessments have since suggested that this market was doubtful to be the only source of the coronavirus outbreak, as a number of the people infected with the virus had not been frequenting the market. Specialists haven’t yet been ready to determine the real source of the virus or maybe confirm whether there was one original reservoir.   How is the virus transmitted?  While it likely originated in animals, the transmission of the new coronavirus from person to person can occur, though some questions on its transmission remain unanswered. According to the WHO spokespeople who skilled MNT queries, “[r]esearchers are still studying the precise parameters of human-to-human transmission.” “In Wuhan at the start of the outbreak, some people became ill from exposure to a source, presumably an animal, carrying the disease. This has been monitored by transmission between people,” they explained, adding: “As with other coronaviruses, the transmission is through the respiratory route, meaning the virus is concentrated within the airways (nose and lungs) and may pass to a different person via droplets from their nose or mouth, for instance. We still need more analysis of the epidemiological data to know the complete extent of this transmission and the way people are infected.” In a press briefing from February 6, WHO consultant Dr. Maria Van Kerkhove said that, for now, “[w]e do know that mild individuals shed virus, we know that severe individuals shed the virus. […] We know that the more symptoms you have, the more likely you are to transmit.” In an interview for the JAMA Network — also broadcast on February 6 — Dr. Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases, said that based on data

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World

Washington state stay-at-home order – Coronavirus outbreak

Washington state stay-at-home order: Inslee extends stay-at-home order through May 31, unveils 4-phase plan to reopen Washington   Gov. Jay Inslee declared on Friday that the statewide stay-at-home request set to lapse Monday was stretched out through May 31. During his Friday evening news meeting, Inslee said organizations would have the option to revive in four stages while changing physical separating measures. There will be at least three weeks between each stage, however, he said a few areas with lower quantities of cases and passings might have the option to open pieces of their economy sooner whenever affirmed by the Department of Health. Stage 1 High-chance populaces: Continue to remain at home, remain sound Outside: Some open-air diversion (chasing, angling, golf, drifting, climbing). Social affairs: None, drive-in otherworldly assistance with one family for each vehicle. Travel: Only fundamental travel. Business/Employers: Essential organizations open, existing development that meet settled upon standards, finishing, car deals, retail( check side get arranges just), vehicle washes, housecleaning, pet walkers. Stage 2 High-hazard populaces: Continue to remain at home, remain sound Open-air: All outside creation including less than 5 individuals outside your family unit (outdoors, sea shores, and so on. Social events: Gather without any than 5 individuals outside your family unit every week. Travel: Limited unnecessary travel inside the nearness of your home. Business/Employers: Remaining assembling, new development, in-home/local administrations (caretakers, housecleaning, and so on.), retail (In-store buys permitted with limitations), land, proficient administrations/office-based organizations (telecommuting remains emphatically supported), hair and nail salons/stylists, eateries <50% limit table size no bigger than 5. Stage 3 High-chance populaces: Continue to remain at home, remain sound Open-air: Outdoor gathering rec. sports exercises (5-50 individuals), recreational offices at <50% limit (open pools, and so forth.). Social events: Allow get-togethers without any than 50 individuals. Travel: Resume trivial travel. Business/Employers: cafés <75% limit/table size no bigger than 10, bars of <25% limit, cinemas at <50% limit, government (telecommuting remains emphatically supported), libraries, historical centers, all different business exercises not yet recorded aside from clubs and occasions with more noteworthy than 50 individuals. Stage 4 High-hazard populaces: Resume open associations, with physical separating Open-air: Resume all recreational movement. Social events: Allow get-togethers >50 individuals. Travel: Continue trivial travel. Business/Employers: Nightclubs, show settings, enormous games, continue unhindered staffing of worksites, however, keep on rehearsing physical removing and great cleanliness.   State authorities are taking a gander at a few measurements, running from the quantity of hospitalizations to the present transmission rate in King County to projections for increments in cases if social removing endeavors were finished today. The senator said testing is going to increase yet we are as yet observing such a large number of cases.   More About Covid” *COVID Prevention – (COVID-19)-Symptoms and Prevention *Covid-19 – Latest Coronavirus outbreak *Quarantine at home- guidance for close contacts *When will a coronavirus vaccine be ready?    Inslee said that while coronavirus passings and hospitalizations were declining in April, the numbers are not low enough to guarantee those numbers will keep on declining. There isn’t one number that can be utilized to settle on a choice about lifting the social removing orders, he included. “We are still not at the level that we can be sure that on the off chance that we discharge our social removing these numbers won’t start to go up too,” he said. The senator has kept up from the beginning that testing will be the way to reviving. The most recent statewide loss of life as detailed by the Department of Health had arrived at 824 passings among 14,637 affirmed coronavirus cases as of 11:59 p.m. Thursday. Here’s a breakdown of a portion of the districts with the most elevated aggregates: King County has 452 passings among 6,274 cases; Snohomish County has 109 passings among 2,453 cases, and Pierce County has 50 passings among 1,339 cases. Snap here to see where different districts in the state stand. Key coronavirus refreshes: There are at any rate 14,637 affirmed coronavirus cases with at any rate 824 passings in Washington, as indicated by the most recent Department of Health numbers as of 11:59 p.m. April 30. Some Washington occupants can apply for crisis money help, on the off chance that they aren’t qualified for different projects. The White House has discharged an 18-page bundle of rules to help states re-open organizations covered by the coronavirus episode. Individuals who have recouped from COVID-19 would now be able to give their plasma to possibly help build up a treatment for the infection. Learn in the event that you are qualified here and discover progressively out about the neighborhood place taking gifts here. All K-12 schools will remain truly shut for the rest of the school year. The state’s more than 1.2 million open and private K-12 understudies will proceed with separation learning until the finish of June. The state DOH and the CDC are suggesting the open wear basic, non-clinical fabric covers or face covers when out in the open spots where social removing may not be kept up. Figure out how to make your own veil here. Thinking about what is as yet open? Discover here. Data from nearby authorities Inslee declared in a Friday question and answer session that the stay-at-home request will stretch out through May 31 and the state will revive in four stages. Minutes after Inslee expanded the stay-at-home request, the city of Seattle said it will keep on working under its condition of common crisis. “Senator Inslee has driven our state in COVID-19 emergency by depending on science and information – broadening the Stay Home, Stay Healthy request and making a staged way to deal with reviving is basic to sparing lives and forestalling an exponential resurgence of the infection. While we have straightened the bend, spared lives and forestalled our social insurance frameworks from being overpowered, Seattle and King County has seen in any event 630 cases and 44 passings over the most recent five days. We need to recall that there are essentially

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World

Coronavirus: WHO defends coronavirus outbreak response

The World Health Organization says it “didn’t waste time” responding to the coronavirus after facing criticism for its handling of the outbreak. Its head Dr Tedros Adhanom Ghebreyesus said the WHO’s declaration of the virus as a world health emergency on 30 January gave “enough time for the remainder of the planet to respond”. At the time there have been only 82 cases outside China and no deaths. Today there are quite 3.2m cases and 234,000 deaths recorded worldwide. US President Donald Trump has said the WHO “really blew” its response and accused it of bias towards China. The US is that the global health body’s largest single funder and President Trump says he will halt funding. Speaking at a press conference on Friday Dr Tedros offered an active defence of how the organisation responded. He insisted the WHO used the time before the declaration wisely, including visiting China to find out more about the virus at its origin.   “More About Covid” *Covid Prevention – (COVID-19)-Symptoms and Prevention *Covid-19 – Latest Coronavirus outbreak *Quarantine at home- guidance for close contacts *When will a coronavirus vaccine be ready?    Dr Tedros confirmed that the pandemic remained a “public health emergency of international concern”, three months after it had been declared one. Such a declaration is formed under an “extraordinary” event and requires a worldwide response. Dr Tedros described “grave” worries over the potential impact of the virus because it accelerates in countries with weaker health systems. Officials said that they had seen worrying increases during a number of those nations – including Haiti, Somalia, and Sudan. The WHO also urged caution among nations relaxing their social distancing measures, stressing the importance of monitoring for brand spanking new jumps in infections as lockdowns are eased.     Ref-https://www.who.int/

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Coronavirus

 Coronavirus Cases Explode in South Korea as China

Coronavirus Coronavirus Cases Explode in South Korea as China Reports 75,000 Infected The spread of the coronavirus that began with cases reported in the city of Wuhan, China, has now spread to many other parts of the world with South Korea the latest nation to report increasing numbers of diagnoses as the rest of East Asia implements strict measures to contain the disease.   It is reported that some 156 people are now infected with the coronavirus in South Korea, joining Japan and Thailand as nations outside of China grappling with the disease in large numbers.   Though a specific treatment course has not yet been established, many doctors are reporting success after treating patients with a combination of “HIV drugs including lopinavir and ritonavir and the antiviral medication oseltamivir,” Pharmaceutical Technology reports.   One point of controversy for many nations combating the disease is the decision to transport potentially infected people back to their home countries for treatment and/or quarantine.   This was most recently highlighted by the scandal in the UK over the government telling British citizens to stay on the Diamond Princess cruise ship when other nations have evacuated their nationals, the BBC reports. But even that is not without controversy as it is now being reported that the United States’ own citizens that were evacuated from the Diamond Princess rode back on a plane with uninfected passengers against the Centers for Disease Control’s recommendations.   Fourteen of these passengers were infected with the virus, the media is reporting, and government officials believed that they could be sectioned off with a plastic tarp and flown back with healthy passengers – a methodology that the CDC questioned. An official involved with the decision-making process behind allowing infected people to fly back with healthy passengers commented that, “It was like the worst nightmare.   Quite frankly, the alternative could have been pulling grandma out in the pouring rain, and that would have been bad, too.” The logic behind removing the passengers from the stranded cruise ship comes from the fact that the number of cases of coronavirus on the ship were going up by an alarming rate.   When asked about the situation on the Diamond Princess, WHO executive director for health emergencies Michael Ryan said, “Obviously, the situation on the ground changed, and clearly there’s been more transmission than expected on the ship. It’s very easy in retrospect to make judgments on public health decisions made at a certain point.”   CDC principal deputy director Anne Schuchat recommended against putting the passengers together on a plane and questioned the administration’s logic in ignoring her agency’s advice, MSN reports.   “CDC did weigh in on this and explicitly recommended against it. We should not be mentioned as having been consulted as it begs the question of what was our advice,” she wrote in an email.   As the virus spreads many experts are pointing out that it is likely to get worse before it gets better. With a fatality rate of 2 in 100 cases and a highly infectious spread rate, the drive to get the disease under control is expected to remain a large health focus for much of 2020.   https://www.bbc.com/news/uk-51555299   https://www.msn.com/en-us/news/us/coronavirus-infected-americans-flown-home-against-cdcs-advice/ar-BB10ddna   https://www.pharmaceutical-technology.com/features/coronavirus-affected-countries-thailand-measures-impact-tourism/      

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Coronavirus

Why do you think BCG-vaccination would protect against COVID-19?

BCG-vaccination   Why do you think BCG-vaccination would protect against COVID-19? Is it real?   COVID-19 is not only successful in infecting people around the world (1) but also obsessed people at the same time with lots of irrelevant things. Who thought this strain of COVID would be stronger than any of its parallel COVID-lines? Who thought this will be highly contagious, spreading with a record speed? Who thought it could be as potent as it stays outside host for hours to days? Who thought it could infect not only immune-compromised people or older people but also people at any age? Who thought this virus could be using healthy human as the best carrier when traveling from country to country? Who thought this not only attacks the respiratory system but also travels through the gastrointestinal tract? Who thought about insisting people “not using face mask” could be dangerous? No one knew any of these questions or if knew, gave wrong solutions! The list is getting longer and longer. As a matter of fact, now BCG-vaccination is becoming a topic around the world in the context of COVID-19 infection whether the western world made a great mistake not practicing BCG-vaccination as part of routine vaccination strategy, with speculation that BCG-vaccination reduces the number of cases of COVID-19 (2). Surprisingly, whether it is true or false, some parts of the world (Asia) are not seeing the aggressive nature of COVID-19 cases (3). Interestingly, most countries in Asia still believe the BCG-vaccination program as one of the important ones protecting against tuberculosis (4). In the Western World, BCG vaccination is no longer recommended due to a lack of protection by BCG-vaccination against pulmonary TB. There are also some side effects of early life BCG vaccination when it comes in the context of HIV infection. The western world stopped using BCG because BCG-vaccination induced immunity is not long-lasting (5), it decays overages. Therefore, revaccination with BCG suggested but was not successful. What is BCG? BCG-vaccine contains live attenuated bacteria. It is given subcutaneously, but it could reach to any place in the body within a short time. Because of this unique ability, BCG-vaccination provides strong immune responses in the lungs even it is administered in a remote place. As I mentioned this vaccine was thought effective against tuberculosis. However, tuberculosis is caused by Mycobacterium tuberculosis which is a virulent pathogen, different from BCG to some extent, especially some of the antigens are missing in BCG that is present in virulent mycobacteria. BCG-specific immunity: When it comes to the vaccination against any pathogen, generally, scientists look for specific immunity to raise by the vaccination. Since tuberculosis causing pathogen is intracellular, meaning immune cells capture mycobacteria and try to kill it while inside by using their machinery. It is believed that T cell-based immunity (type-1) is very effective in killing tuberculosis pathogens. Since this infection is respiratory, people thought of inducing specific immunity by giving BCG-vaccination through the intranasal route. Unfortunately, the intranasal route of administration of BCG is not safe, especially for children. One, remarkable observation is that even BCG- vaccination is not very effective against pulmonary (lung) TB, this still very effective against other forms of tuberculosis, not formed in the lungs. This is why third world countries still keep BCG as their routine vaccination strategy.   Why BCG-induced immunity would be effective against COVID-19? COVID-19 is a completely different pathogen and does not show any similarities with tuberculosis or BCG. There is no scientific evidence yet showing BCG-induced immunity could prevent COVID-19 infection further to spread. Like many other COVIDs, COVID-19 is using a similar route to attack humans, displaying symptoms like the common cold. The only difference with COVID-19 is that it could lead to aggressive lung infection and results in pneumonia-like symptoms. To prevent viral infection, scientists would allow natural immunity to develop because there is no effective medication or successful vaccines available against such flu-like virus. Every year we received vaccines against flu (influenza) which are either not effective or sometimes only effective partially. Interestingly, this virus acquires genetic modification so rapidly and because of this fact ultimately one particular vaccine against the same virus may not work for the next year. This is a common problem and perhaps one biggest challenge in the development of a vaccine against COVID-19 (6). Now, when a specific vaccine is not working against COVIDs, how one could think BCG-vaccination will provide protection against another pathogen like COVID-19? Immune response either naturally induced or vaccination-induced is very complex in nature. Generally, two types of immunity can be seen: innate (rapid and non-specific) and adaptive (specific-long-lived). The only advantage of BCG-vaccination is that due to the nature of this vaccine, it induces very strong innate immunity and it is stronger than any other form of vaccines in history. At the same time, BCG could also act as an adjuvant, meaning could help other vaccines when giving at the same time or in a strategy called prime-boost vaccination. BCG can work as a very good candidate to prime the immune system. When the term ‘priming’ comes, it induces strong innate immune responses, which is generally important to let adaptive immune cells to know. This collaborative effort is very necessary to use all of the tools of the immune system in order to generate an effective immune response. Virus-induced natural immunity: Most of these seasonal flu-virus induced immunity is developed with a week or two. The scientist also aims for inducing humoral (a specific antibody) immune response when targeting a vaccine against any of this virus. Since a majority of the population are naturally protective against common flu, it is thought that antibody-mediated protection is the key, because specific antibody can neutralize the virus. Thus, in the context of BCG-vaccination, one key question is does BCG-vaccination induce specific antibody responses against COVID-19? The answer is likely ‘NO’. But one possibility is that BCG-vaccination is very unique in the sense that this could induce lots of cross-reactive

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Science

COVID-19-NASA Satellite Spots Less Air Pollution

Novel Coronavirus outbreak – NASA Satellite found Less Air Pollution on US East Coast And China. Over the past several weeks, NASA satellite estimations have revealed significant reductions in pollution over the significant metropolitan territories of the Northeast United States. Comparative decreases have been seen in different regions of the world. These ongoing upgrades in air quality have come at a significant expense, as communities struggle with widespread lockdowns and shelter-in-place orders as a result of the spread of COVID-19. Nitrogen dioxide, primarily emitted from burning fossil fuels for transportation and electricity generation, is often used as an indicator of changes in human movement. The pictures above show average concentrations of atmospheric nitrogen dioxide as measured by the Ozone Monitoring Instrument (OMI) on NASA’s Aura satellite, as processed by a team at NASA’s Goddard Space Flight Center, Greenbelt, Maryland. The left image within the slider shows the typical concentration in March of 2015-19, while the proper image within the slider shows the typical concentration measured in March of this year.   Though differences in climate from year to year source differences within the monthly means for individual years, March 2020 shows lowest bottom monthly atmospheric nitrogen dioxide levels of any March during the OMI data evidence, which spans 2005 to the present. In fact, the info indicates that the nitrogen dioxide levels in March 2020 are about 30% lower on the average across the region of the I-95 corridor from Washington, DC to Boston than in comparison to the March mean of 2015-19. Further investigation will be required to thoroughly measure the measure of the adjustment in nitrogen dioxide levels related to changes in emanations versus regular varieties in climate. If processed and interpreted carefully, nitrogen dioxide levels observed from space function an efficient proxy for nitrogen dioxide levels at surface, though there’ll likely be differences within the measurements from space and people made at ground level. It’s also important to notice that satellites that measure nitrogen dioxide cannot see through clouds, so all data shown is for days with low cloudiness. Such nuances within the data make long-term records vital in understanding changes like those shown during this image. COVID-19-NASA Satellite Air Pollution- China NASA and European Space Agency (ESA) contamination observing satellites have distinguished critical declines in nitrogen dioxide (NO2) over China. There’s evidence that the change is a minimum of partly associated with the economic slowdown following the outbreak of coronavirus. At the end of 2019, clinical experts in Wuhan, China, were treating many pneumonia cases that had an obscure source. Days later, researchers confirmed the illnesses were caused by a novel coronavirus (COVID-19). By January 23, 2020, Chinese authorities had shut down transportation going into and out of Wuhan, also as local businesses, so as to scale back the spread of the disease. It was the first of several quarantines set up in the country and around the world. The maps on this page show concentration of nitrogen dioxide, a noxious gas emitted by automobiles, power plants, and industrial facilities. The maps above show NO2 values across China from January 1-20, 2020 (preceding the isolate) and February 10-25 (during the isolate). The information was gathered by the Tropospheric Monitoring Instrument (TROPOMI) on ESA’s Sentinel-5 satellite. A related sensor, the Ozone Monitoring Instrument (OMI) on NASA’s Aura satellite, has been making comparable estimations. COVID-19-NASA Satellite This is that the first time I ever have seen such a dramatic drop-off over such a good area for a selected event,” said Fei Liu, an air quality researcher at NASA’s Goddard Space Flight Center. Liu recalls seeing a drop by NO2 over several countries during the economic recession that began in 2008, but the decrease was gradual. Scientists also observed a big reduction around Beijing during the 2008 Olympics, but the effect was mostly localized around that city, and pollution levels rose again once the Olympics ended. COVID-19-NASA Satellite

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Coronavirus

Novel Coronavirus (COVID-19)-Symptoms and Prevention

What Is the Coronavirus (COVID-19)? A coronavirus is a kind of virus that often happens in animals. Sometimes, it can spread to humans. This is rare. In December 2019, a new coronavirus started spreading. Specialists think people first caught the virus at a fish and live animal marketplace. Now it is spreading from person to person. According to the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO), common coronavirus symptoms can include:     Fever     Cough (usually dry)     Shortness of breath     Feeling tired Other less common symptoms can include:     Stuffy or runny nose     Aches and pains     Sore throat     Headaches     Diarrhea or nausea The CDC believes symptoms may appear two to 14 days after coming in contact with the virus. WHO has declared it a global pandemic (an outbreak of a new virus that spreads easily). How Can I Tell the Variance Between the Coronavirus, the Flu, Cold or Seasonal Allergies? There are some symptoms that are similar between these respiratory illnesses. This chart can help you figure out if you may be feeling symptoms of allergies or a respiratory illness like COVID-19. If you have a fever and a cough, call your doctor. If you have seasonal allergies, there are things you can do to treat at home. These conditions may intensify asthma, so it’s imperative to continue taking your asthma control meds. Data is as yet evolving. We will refresh this diagram as new proof comes out. How Does the Coronavirus Spread? The virus is spread through coughing (or sneezing). The infection will be in droplets that are coughed out into the air. These are overwhelming droplets and they rapidly tumble to the ground/surface underneath.People who are within 1 to 2 meters (3 to 6 feet) of somebody who is sick with the coronavirus might be inside the zone that droplets can reach. If someone who is sick coughs on or nearby your face, you may get infected. This is the reason the CDC suggests that everybody should cough/sneeze into their elbows or tissue and discard it and wash their hands. people who are wiped out ought to likewise wear a cover to help stop the spread of ailment. The coronavirus may likewise live on surfaces that people have coughed on. If you touch a surface with the virus on it and then touch your mouth, nose or eyes, you might get sick.   Who Is at Risk From the Coronavirus? At this period, there is little data about how the novel coronavirus distresses people with asthma. One investigation of 140 cases demonstrated no connection to asthma.1 However, we realize that asthma has worsened with different anxieties of coronavirus. As indicated by the WHO and the CDC, the most elevated hazard bunches include:   People who have traveled in from a country with a Level 3 Travel Notice People caring for someone who is ill with the coronavirus People over age 65 People who are pregnant People with chronic medical conditions such as: High blood pressure Heart disease Diabetes Renal failure Liver disease Immunocompromised people, such as those on cancer treatments People with a body mass index over 40 Asthma (and other lung diseases) people with asthma should play it safe when any kind of respiratory ailment is spreading in their locale. The CDC has released instructions for people at high risk (including people with asthma): Stock up on supplies (a 14 to 30 day supply) Take steps to keep a distance from others (social distancing, about 6 feet) Avoid people who are sick, limit close contact and wash your hands often Avoid crowds as much as possible Avoid non-essential travel Clean and disinfect your home and car regularly, especially items you touch often like doorknobs, light switches, cell phones, car door handles and steering wheels, etc. If there is an outbreak in your local community, the CDC also recommends you stay home as much as possible. Try to find ways to have food and supplies delivered to your home. In the U.S., flu activity is still high. If you get sick, it could be the flu unless you live in a coronavirus outbreak area. If you have symptoms of a cough or fever, call your doctor. There are antiviral treatments available for the flu. How Can I Avoid Getting the Coronavirus and Other Respiratory Infections? The steps you take to avoid the flu and other respiratory infections will also help protect you from the coronavirus:   Wash your hands often with soap and warm water for 20 to 30 seconds, always after coughing or sneezing. If you don’t have access to running water, use an alcohol-based hand cleanser that is at least 60% alcohol.     Don’t touch your eyes, nose or mouth.     Stay away from people who are sick or have been in contact with someone who is sick.     Don’t share makeup, food, dishes or eating utensils.     Take your daily asthma medicines to keep your asthma under control. Spring pollen is increasing across the U.S. too. Seasonal allergies can affect people with allergic asthma. If pollen allergies trigger asthma symptoms for you, be sure to follow your allergy treatment plan to keep your allergies under control to prevent asthma episodes or attacks. The most important way you can protect yourself right now is to keep your asthma under control. If your asthma is not under control, call your doctor right away. If you do get sick, call your doctor and follow your Asthma Action Plan. There is no vaccine for the new coronavirus. Get the flu shot if you haven’t already – it’s not too late to protect yourself from the flu. The flu season can last as late as May. Wearing a mask to protect yourself from getting sick is not recommended by the WHO nor the CDC. Only people who are sick or people who are caregivers of people who are sick should wear masks. If you plan to travel, check

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Coronavirus

Coronavirus: US Navy captain appeals for help over outbreak

  Coronavirus Outbreak: US Navy Ship The captain of a US Navy aircraft carrying warship confronting a developing coronavirus outbreak has requested authorization to isolate the greater part of his approximately 5,000 group individuals on the Pacific Island of Guam, where it is at present docked. Key focuses: The spread of coronavirus on-board is fast-tracking, the captain says The nuclear-powered carrier lacks quarantine and isolation facilities USA Navy officials are trying to find appropriate accommodation on Guam The move would remove the USS Theodore Roosevelt from obligation with an end goal to spare lives, yet it might be hard for the island of only 164,000 individuals to suit the group.Guam has just 250 staffed emergency clinic beds, and at present has more COVID-19 cases than some other nation or region in the Pacific district, barring Australia, New Zealand, and Hawaii. In a four-page memo to Navy leaders, the captain of the nuclear-powered warship said the spread of the disease was continuous and rushing and said that evacuating everything except 10 percent of the team is a “necessary risk” so as to stop the spread of the virus. Captain Brett Crozier wrote that the carrier needed enough isolate and isolation facilities and cautioned and warned the present approach would slow but fail to eliminate the virus. “We are not at war. Sailors do not need to die,” he said. “On the off chance that we don’t act now, we are neglecting to appropriately deal with our most confided in resource — our mariners.”Acting USA Navy Secretary Thomas Modly said he had found out about the letter, and that the Navy has been working for a few days to get the mariners off the ship in Guam. Mr Modly said Guam needed more beds, and the Navy was in talks with the local government to use hotels and set up tents.[su_quote] “We don’t disagree with [the commanding officer] on that ship, and we’re doing it in a very methodical way because it’s not the same as a cruise ship,” he told CNN. “That USA navy ship has deadly implements on it, it has an airplane on it.” A US Navy official, who addressed the Associated Press on the state of obscurity to examine inward considerations, said Captain Crozier wants more isolated housing for the crew and that Navy leadership is reviewing options to ensure the health and safety of the crew. The carrier, like other Navy ships, is exposed to infectious disease spread given its close quarters — the massive ship is more than 300 meters long, with sailors spread out across a labyrinth of decks, connected by steep ladder-like stairs and narrow corridors. Each US Navy ship has a 1,000-bed limit and is kept an eye on by military medical staff, requiring about up to seven days to activate those workforces from over the deployment-ready and hold powers.  Pentagon authorities have focused on that a large number of the save medical workforce that would be called up to staff mobile hospitals or Mercy and Comfort would be somewhat pulled from civilian medical facilities. Recruited sailors and officers have isolated living quarters, but they habitually grab their food from crowded buffet lines and eat at tables joined end-to-end. A carrier attendance is central to the US Navy’s operations in the Asia Pacific region amid ongoing tensions with China, over issues including its militarization of disputed areas of the South China Sea.

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